| Item Type | Name |
|
Concept
|
Combined Modality Therapy
|
|
Concept
|
Cytological Techniques
|
|
Concept
|
Congresses as Topic
|
|
Concept
|
T-Lymphocytes, Helper-Inducer
|
|
Concept
|
Immune Tolerance
|
|
Concept
|
Lymphocyte Culture Test, Mixed
|
|
Concept
|
Mice, Transgenic
|
|
Concept
|
Neoplasm Transplantation
|
|
Concept
|
Radioactive Tracers
|
|
Concept
|
Time Factors
|
|
Concept
|
Tomography, X-Ray Computed
|
|
Concept
|
Transcription, Genetic
|
|
Concept
|
Interferon Type I
|
|
Concept
|
Tryptophan
|
|
Concept
|
Biomarkers, Tumor
|
|
Concept
|
Tumor Necrosis Factor-alpha
|
|
Concept
|
Ion Transport
|
|
Concept
|
Testis
|
|
Concept
|
Transduction, Genetic
|
|
Concept
|
Hematopoietic Stem Cell Transplantation
|
|
Concept
|
Th1 Cells
|
|
Concept
|
Cell Culture Techniques
|
|
Concept
|
Reverse Transcriptase Polymerase Chain Reaction
|
|
Concept
|
Tumor Cells, Cultured
|
|
Concept
|
Transforming Growth Factor beta
|
|
Concept
|
CD4-Positive T-Lymphocytes
|
|
Concept
|
Lymphocytes, Tumor-Infiltrating
|
|
Concept
|
Stem Cell Transplantation
|
|
Concept
|
T-Lymphocyte Subsets
|
|
Concept
|
Protein Structure, Tertiary
|
|
Concept
|
Receptors, Antigen, T-Cell, alpha-beta
|
|
Concept
|
Treatment Outcome
|
|
Concept
|
Gene Transfer Techniques
|
|
Concept
|
CD8-Positive T-Lymphocytes
|
|
Concept
|
Thapsigargin
|
|
Concept
|
Th2 Cells
|
|
Concept
|
Transgenes
|
|
Concept
|
Tumor Necrosis Factor Receptor Superfamily, Member 9
|
|
Concept
|
Receptor Protein-Tyrosine Kinases
|
|
Concept
|
Genes, T-Cell Receptor
|
|
Concept
|
Positron-Emission Tomography
|
|
Concept
|
Tumor Escape
|
|
Concept
|
Adoptive Transfer
|
|
Concept
|
Tissue Distribution
|
|
Concept
|
Molecular Targeted Therapy
|
|
Concept
|
Natural Killer T-Cells
|
|
Concept
|
Cell Engineering
|
|
Concept
|
T-Lymphocytes, Cytotoxic
|
|
Concept
|
Transfection
|
|
Concept
|
Electrophoresis, Gel, Two-Dimensional
|
|
Concept
|
Genetic Therapy
|
|
Concept
|
Imaging, Three-Dimensional
|
|
Concept
|
Genes, Transgenic, Suicide
|
|
Concept
|
T-Lymphocytes, Regulatory
|
|
Concept
|
TNF-Related Apoptosis-Inducing Ligand
|
|
Concept
|
Tumor Microenvironment
|
|
Concept
|
Lectins, C-Type
|
|
Concept
|
Cell Line, Tumor
|
|
Concept
|
ZAP-70 Protein-Tyrosine Kinase
|
|
Concept
|
T Cell Transcription Factor 1
|
|
Concept
|
Clinical Trials as Topic
|
|
Concept
|
Receptors, Antigen, T-Cell
|
|
Concept
|
T-Lymphocytes
|
|
Concept
|
Thymus Gland
|
|
Concept
|
Transplantation, Autologous
|
|
Concept
|
Signal Transduction
|
|
Concept
|
Coculture Techniques
|
|
Academic Article
|
A novel AKT1 mutant amplifies an adaptive melanoma response to BRAF inhibition.
|
|
Academic Article
|
Acquired resistance and clonal evolution in melanoma during BRAF inhibitor therapy.
|
|
Academic Article
|
MHC-I-restricted melanoma antigen specific TCR-engineered human CD4+ T cells exhibit multifunctional effector and helper responses, in vitro.
|
|
Academic Article
|
Active Immunotherapy of Cancer.
|
|
Academic Article
|
CTLA4 blockade broadens the peripheral T-cell receptor repertoire.
|
|
Academic Article
|
Adoptive transfer of MART-1 T-cell receptor transgenic lymphocytes and dendritic cell vaccination in patients with metastatic melanoma.
|
|
Academic Article
|
Exposure to a histone deacetylase inhibitor has detrimental effects on human lymphocyte viability and function.
|
|
Academic Article
|
Efficient identification of neoantigen-specific T-cell responses in advanced human ovarian cancer.
|
|
Academic Article
|
A clinical microchip for evaluation of single immune cells reveals high functional heterogeneity in phenotypically similar T cells.
|
|
Academic Article
|
WHSC1/NSD2 regulates immune infiltration in prostate cancer.
|
|
Academic Article
|
CTLA4 blockade increases Th17 cells in patients with metastatic melanoma.
|
|
Academic Article
|
Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation.
|
|
Academic Article
|
Melanoma whole-exome sequencing identifies (V600E)B-RAF amplification-mediated acquired B-RAF inhibitor resistance.
|
|
Academic Article
|
A rare population of tumor antigen-specific CD4+CD8+ double-positive aß T lymphocytes uniquely provide CD8-independent TCR genes for engineering therapeutic T cells.
|
|
Academic Article
|
Multifunctional T-cell analyses to study response and progression in adoptive cell transfer immunotherapy.
|
|
Academic Article
|
HSV-sr39TK positron emission tomography and suicide gene elimination of human hematopoietic stem cells and their progeny in humanized mice.
|
|
Academic Article
|
Cellular Immunotherapy in the Treatment of Hematopoietic Malignancies.
|
|
Academic Article
|
The impact of ex vivo clinical grade activation protocols on human T-cell phenotype and function for the generation of genetically modified cells for adoptive cell transfer therapy.
|
|
Academic Article
|
Modulation of cell signaling networks after CTLA4 blockade in patients with metastatic melanoma.
|
|
Academic Article
|
Rapid Construction of Antitumor T-cell Receptor Vectors from Frozen Tumors for Engineered T-cell Therapy.
|
|
Academic Article
|
BRAF inhibitor vemurafenib improves the antitumor activity of adoptive cell immunotherapy.
|
|
Academic Article
|
Mature neutrophils suppress T cell immunity in ovarian cancer microenvironment.
|
|
Academic Article
|
Natural killer T cells in advanced melanoma patients treated with tremelimumab.
|
|
Academic Article
|
Kinetic phases of distribution and tumor targeting by T cell receptor engineered lymphocytes inducing robust antitumor responses.
|
|
Academic Article
|
Dendritic cell-based immunotherapy in prevention and treatment of renal cell carcinoma: efficacy, safety, and activity of Ad-GM·CAIX in immunocompetent mouse models.
|
|
Academic Article
|
CTLA4 blockade induces frequent tumor infiltration by activated lymphocytes regardless of clinical responses in humans.
|
|
Academic Article
|
Antitumor effects of the investigational selective MEK inhibitor TAK733 against cutaneous and uveal melanoma cell lines.
|
|
Academic Article
|
Transduction of acute myeloid leukemia cells with third generation self-inactivating lentiviral vectors expressing CD80 and GM-CSF: effects on proliferation, differentiation, and stimulation of allogeneic and autologous anti-leukemia immune responses.
|
|
Academic Article
|
Inhibition of CSF-1 receptor improves the antitumor efficacy of adoptive cell transfer immunotherapy.
|
|
Academic Article
|
Single-cell analysis resolves the cell state transition and signaling dynamics associated with melanoma drug-induced resistance.
|
|
Academic Article
|
Antitumor activity from antigen-specific CD8 T cells generated in vivo from genetically engineered human hematopoietic stem cells.
|
|
Academic Article
|
A cloning method for caspase substrates that uses the yeast two-hybrid system: cloning of the antiapoptotic gene gelsolin.
|
|
Academic Article
|
Gelsolin inhibits apoptosis by blocking mitochondrial membrane potential loss and cytochrome c release.
|
|
Academic Article
|
Human antigen-specific regulatory T cells generated by T cell receptor gene transfer.
|
|
Academic Article
|
Lentiviral vector-mediated autonomous differentiation of mouse bone marrow cells into immunologically potent dendritic cell vaccines.
|
|
Academic Article
|
Lentiviral vectors with CMV or MHCII promoters administered in vivo: immune reactivity versus persistence of expression.
|
|
Academic Article
|
Measurement and Quantitative Characterization of Whole-Body Pharmacokinetics of Exogenously Administered T Cells in Mice.
|
|
Academic Article
|
Distinct immunological mechanisms of CTLA-4 and PD-1 blockade revealed by analyzing TCR usage in blood lymphocytes.
|
|
Academic Article
|
Improved antitumor activity of immunotherapy with BRAF and MEK inhibitors in BRAF(V600E) melanoma.
|
|
Academic Article
|
A novel series of conferences tackling the hurdles confronting the translation of novel cancer immunotherapies.
|
|
Academic Article
|
Human gelsolin prevents apoptosis by inhibiting apoptotic mitochondrial changes via closing VDAC.
|
|
Academic Article
|
CD4+CD25- T cells transduced to express MHC class I-restricted epitope-specific TCR synthesize Th1 cytokines and exhibit MHC class I-restricted cytolytic effector function in a human melanoma model.
|
|
Academic Article
|
The TLR-7 agonist, imiquimod, enhances dendritic cell survival and promotes tumor antigen-specific T cell priming: relation to central nervous system antitumor immunity.
|
|
Academic Article
|
Gelsolin functions as a metastasis suppressor in B16-BL6 mouse melanoma cells and requirement of the carboxyl-terminus for its effect.
|
|
Academic Article
|
Potent maturation of monocyte-derived dendritic cells after CD40L lentiviral gene delivery.
|
|
Academic Article
|
siRNA knockdown of ribonucleotide reductase inhibits melanoma cell line proliferation alone or synergistically with temozolomide.
|
|
Academic Article
|
Decitabine immunosensitizes human gliomas to NY-ESO-1 specific T lymphocyte targeting through the Fas/Fas ligand pathway.
|
|
Academic Article
|
The use of lentiviral vectors in gene therapy of leukemia: combinatorial gene delivery of immunomodulators into leukemia cells by state-of-the-art vectors.
|
|
Academic Article
|
Analysis of the value of empiric vancomycin administration in febrile neutropenia occurring after autologous peripheral blood stem cell transplants.
|
|
Academic Article
|
Preexisting MEK1 exon 3 mutations in V600E/KBRAF melanomas do not confer resistance to BRAF inhibitors.
|
|
Academic Article
|
RAS mutations in cutaneous squamous-cell carcinomas in patients treated with BRAF inhibitors.
|
|
Academic Article
|
Monocytes transduced with lentiviral vectors expressing hepatitis C virus non-structural proteins and differentiated into dendritic cells stimulate multi-antigenic CD8(+) T cell responses.
|
|
Academic Article
|
Synthesis, Tumor Specificity, and Photosensitizing Efficacy of Erlotinib-Conjugated Chlorins and Bacteriochlorins: Identification of a Highly Effective Candidate for Photodynamic Therapy of Cancer.
|
|
Academic Article
|
T cell receptor (TCR)-transgenic CD8 lymphocytes rendered insensitive to transforming growth factor beta (TGFß) signaling mediate superior tumor regression in an animal model of adoptive cell therapy.
|
|
Academic Article
|
Immune rejection in a humanized model of murine prostate cancer.
|
|
Academic Article
|
Molecular mechanism of MART-1+/A*0201+ human melanoma resistance to specific CTL-killing despite functional tumor-CTL interaction.
|
|
Academic Article
|
Host immunity contributes to the anti-melanoma activity of BRAF inhibitors.
|
|
Academic Article
|
Differential sensitivity of melanoma cell lines with BRAFV600E mutation to the specific Raf inhibitor PLX4032.
|
|
Academic Article
|
Immunosensitization with a Bcl-2 small molecule inhibitor.
|
|
Academic Article
|
Isolation of cDNAs that cover the entire coding region of a novel human protein D40.
|
|
Academic Article
|
Tunable-combinatorial mechanisms of acquired resistance limit the efficacy of BRAF/MEK cotargeting but result in melanoma drug addiction.
|
|
Academic Article
|
Adoptive cell transfer of T-cell receptor-engineered lymphocytes: lessons from recent modeling.
|
|
Academic Article
|
Inhibition of colony stimulating factor-1 receptor improves antitumor efficacy of BRAF inhibition.
|
|
Academic Article
|
Modular nucleic acid assembled p/MHC microarrays for multiplexed sorting of antigen-specific T cells.
|
|
Academic Article
|
Frequent expression of new cancer/testis gene D40/AF15q14 in lung cancers of smokers.
|
|
Academic Article
|
Making dendritic cells from the inside out: lentiviral vector-mediated gene delivery of granulocyte-macrophage colony-stimulating factor and interleukin 4 into CD14+ monocytes generates dendritic cells in vitro.
|
|
Academic Article
|
Engineered microenvironment for the study of myofibroblast mechanobiology.
|
|
Academic Article
|
CXCR6 by increasing retention of memory CD8+ T cells in the ovarian tumor microenvironment promotes immunosurveillance and control of ovarian cancer.
|
|
Academic Article
|
Engineering tumor stromal mechanics for improved T cell therapy.
|
|
Academic Article
|
Metabolic adaptation of ovarian tumors in patients treated with an IDO1 inhibitor constrains antitumor immune responses.
|
|
Academic Article
|
Tcf-1 protects anti-tumor TCR-engineered CD8+ T-cells from GzmB mediated self-destruction.
|
|
Academic Article
|
Correction to: Tcf-1 protects anti-tumor TCR-engineered CD8+ T-cells from GzmB mediated self-destruction.
|
|
Academic Article
|
Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses.
|
|
Concept
|
Cell- and Tissue-Based Therapy
|
|
Concept
|
In Vitro Techniques
|
|
Academic Article
|
Implementation of a gene therapy education initiative by the ASGCT and Muhimbili University of Health and Allied Sciences.
|